Computational Optics for Biomedical Imaging (COBI) Lab

We are hiring!

We are looking for talented students and postdocs to join our lab! The goal of my lab is to develop advanced imaging techniques by jointly develop optical systems and computational algorithms. A potential candidate should have a research interest in computational optics, biophotonics, and microscopy imaging, and possess background knowledge in optics, image processing, Fourier optics, and optimization. Please contact Dr. Yi Xue at [email protected] with your CV attached if you are interested.

News

7/1/2026 Dr. Xue received tenure and was promoted to Associate Professor!

10/23/2025 Our new paper "Recover Biological Structure from Sparse-View Diffraction Images with Neural Volumetric Prior" is published in the Proceedings of the IEEE/CVF International Conference on Computer Vision (ICCV)!

5/30/2025 Received NSF CAREER Award for multimodal imaging of neurovasculature coupling using multiphoton-phase microscopy.

3/11/2025 Our new paper "Scattering correction through Fourier-domain intensity coupling in two-photon microscopy (2P-FOCUS)" is published on OPTICA Photonics Research!

11/19/2024 Congratulations to Renzhi He for winning SPIE Photonics West Travel Award!

8/1/2024 We received $1.9 million from the NIH MIRA Award over five years to develop computational two-photon microscopy with scattering correction for deep tissue imaging.

1/25/2024 Congratulations to Yucheng (Steven) Li for winning the student travel award for presenting 2P-BRIEF at SPIE Photonics West 2024!